Review



sting inhibitor h151  (MedChemExpress)


Bioz Verified Symbol MedChemExpress is a verified supplier
Bioz Manufacturer Symbol MedChemExpress manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 99
      Buy from Supplier

    Structured Review

    MedChemExpress sting inhibitor h151
    STING loss- and gain- of function studies support a growth-restraining role in PEL. (A) BCBL1 and (B) BC3 cells were treated with 5 µM <t>H151</t> for 72 hours and subjected to CellTiter-Glo assay. Western blot of STING overexpression 48 hours after electroporation of 100 ng pcDNA3.1 (EV) or 50-100 ng STING plasmid in (C) BCBL1 and (D) BC3 cells. CellTiter-Glo assay in (E) BCBL1 and (F) BC3 cells at 72 hours after EV or STING plasmid electroporation. Data is represented as relative luminescence units. Data (A-B, E-F) are presented as mean ± SD. * indicates p<0.05; ** indicates p<0.01; *** indicates p<0.001 by Student’s t-test.
    Sting Inhibitor H151, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 99/100, based on 217 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/sting+inhibitor+h151/H-151/pmc13183639-91-9-12
    Average 99 stars, based on 217 article reviews
    sting inhibitor h151 - by Bioz Stars, 2026-09
    99/100 stars

    Images

    1) Product Images from "STING inhibits viral lytic reactivation and cell growth in primary effusion lymphoma"

    Article Title: STING inhibits viral lytic reactivation and cell growth in primary effusion lymphoma

    Journal: Frontiers in Immunology

    doi: 10.3389/fimmu.2026.1823240

    STING loss- and gain- of function studies support a growth-restraining role in PEL. (A) BCBL1 and (B) BC3 cells were treated with 5 µM H151 for 72 hours and subjected to CellTiter-Glo assay. Western blot of STING overexpression 48 hours after electroporation of 100 ng pcDNA3.1 (EV) or 50-100 ng STING plasmid in (C) BCBL1 and (D) BC3 cells. CellTiter-Glo assay in (E) BCBL1 and (F) BC3 cells at 72 hours after EV or STING plasmid electroporation. Data is represented as relative luminescence units. Data (A-B, E-F) are presented as mean ± SD. * indicates p<0.05; ** indicates p<0.01; *** indicates p<0.001 by Student’s t-test.
    Figure Legend Snippet: STING loss- and gain- of function studies support a growth-restraining role in PEL. (A) BCBL1 and (B) BC3 cells were treated with 5 µM H151 for 72 hours and subjected to CellTiter-Glo assay. Western blot of STING overexpression 48 hours after electroporation of 100 ng pcDNA3.1 (EV) or 50-100 ng STING plasmid in (C) BCBL1 and (D) BC3 cells. CellTiter-Glo assay in (E) BCBL1 and (F) BC3 cells at 72 hours after EV or STING plasmid electroporation. Data is represented as relative luminescence units. Data (A-B, E-F) are presented as mean ± SD. * indicates p<0.05; ** indicates p<0.01; *** indicates p<0.001 by Student’s t-test.

    Techniques Used: Glo Assay, Western Blot, Over Expression, Electroporation, Plasmid Preparation

    Related Articles

    Mouse Assay:

    Article Title: Mechanistic Study of cGAS-STING Pathway–Induced Pyroptosis in Corneal Epithelial Cells in Keratoconjunctivitis Sicca
    Article Snippet: .. Mice assigned to the intervention groups received intraperitoneal injections of the STING inhibitor H151 (HY-112693, MedChem Express, Monmouth Junction, NJ, USA) once daily for seven consecutive days, administered 1h before each scopolamine hydrobromide injection. ..

    Injection:

    Article Title: Mechanistic Study of cGAS-STING Pathway–Induced Pyroptosis in Corneal Epithelial Cells in Keratoconjunctivitis Sicca
    Article Snippet: .. Mice assigned to the intervention groups received intraperitoneal injections of the STING inhibitor H151 (HY-112693, MedChem Express, Monmouth Junction, NJ, USA) once daily for seven consecutive days, administered 1h before each scopolamine hydrobromide injection. ..

    CCK-8 Assay:

    Article Title: Targeted Nanosensitizer-Augmented Sono-Immunotherapy with STING Agonist to Remodel the Immune Microenvironment in Hepatocellular Carcinoma.
    Article Snippet: .. Cell counting kit-8 (CCK- 8) assay kit, STING inhibitor H151, and 2',7'-dichlorodihydrofluorescein diacetate (DCFHDA) were obtained from MedChemExpress (Shanghai, China). .. Calcein AM/propidium iodide (PI) cell viability/cytotoxicity assay kit, Lyso-Tracker Green, Hoechst 33342 staining solution, and enhanced ATP assay kit were provided by Beyotime Biotechnology (Jiangsu, China).

    Inhibition:

    Article Title: The cGAS-STING-interferon regulatory factor 7 pathway regulates neuroinflammation in Parkinson’s disease
    Article Snippet: To assess changes in IRF7 expression in vitro , BV2 cells were cultured in 6-well plates at a density of 5 × 10 5 cells/mL, then exposed to 0, 10, 20, or 50 μM MPP + (MCE, Shanghai, China, Cat# HY-W008719) for 24 hours. .. To investigate the potential neuroprotective effects of cGAS or STING inhibition, cells were pre-incubated with the selective cGAS inhibitor RU.521 (2 μM; Cat# HY-114180, MCE) or the STING inhibitor H151 (5 μM; Cat# HY-112693, MCE) for 12 hours before MPP + (20 μM) exposure (Hinkle et al., 2022; Wu et al., 2023). .. A similar volume of phosphate-buffered saline (PBS) or dimethyl sulfoxide (BBI, Shanghai, China, Cat# A600163-0250) was used as a control.



    Similar Products

    sting inhibitor h151  (MedChemExpress)
    99
    MedChemExpress sting inhibitor h151
    STING loss- and gain- of function studies support a growth-restraining role in PEL. (A) BCBL1 and (B) BC3 cells were treated with 5 µM <t>H151</t> for 72 hours and subjected to CellTiter-Glo assay. Western blot of STING overexpression 48 hours after electroporation of 100 ng pcDNA3.1 (EV) or 50-100 ng STING plasmid in (C) BCBL1 and (D) BC3 cells. CellTiter-Glo assay in (E) BCBL1 and (F) BC3 cells at 72 hours after EV or STING plasmid electroporation. Data is represented as relative luminescence units. Data (A-B, E-F) are presented as mean ± SD. * indicates p<0.05; ** indicates p<0.01; *** indicates p<0.001 by Student’s t-test.
    Sting Inhibitor H151, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/sting+inhibitor+h151/H-151/pmc13183639-91-9-12
    Average 99 stars, based on 1 article reviews
    sting inhibitor h151 - by Bioz Stars, 2026-09
    99/100 stars
    		  Buy from Supplier
    experiment invivogen tlrl bx7 h151 sting inhibitor  (InvivoGen)
    96
    InvivoGen experiment invivogen tlrl bx7 h151 sting inhibitor
    STING loss- and gain- of function studies support a growth-restraining role in PEL. (A) BCBL1 and (B) BC3 cells were treated with 5 µM <t>H151</t> for 72 hours and subjected to CellTiter-Glo assay. Western blot of STING overexpression 48 hours after electroporation of 100 ng pcDNA3.1 (EV) or 50-100 ng STING plasmid in (C) BCBL1 and (D) BC3 cells. CellTiter-Glo assay in (E) BCBL1 and (F) BC3 cells at 72 hours after EV or STING plasmid electroporation. Data is represented as relative luminescence units. Data (A-B, E-F) are presented as mean ± SD. * indicates p<0.05; ** indicates p<0.01; *** indicates p<0.001 by Student’s t-test.
    Experiment Invivogen Tlrl Bx7 H151 Sting Inhibitor, supplied by InvivoGen, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/sting+inhibitor+h151/H-151/pm41973907-274-37-38
    Average 96 stars, based on 1 article reviews
    experiment invivogen tlrl bx7 h151 sting inhibitor - by Bioz Stars, 2026-09
    96/100 stars
    		  Buy from Supplier
    sting inhibitor h 151  (InvivoGen)
    96
    InvivoGen sting inhibitor h 151
    STING loss- and gain- of function studies support a growth-restraining role in PEL. (A) BCBL1 and (B) BC3 cells were treated with 5 µM <t>H151</t> for 72 hours and subjected to CellTiter-Glo assay. Western blot of STING overexpression 48 hours after electroporation of 100 ng pcDNA3.1 (EV) or 50-100 ng STING plasmid in (C) BCBL1 and (D) BC3 cells. CellTiter-Glo assay in (E) BCBL1 and (F) BC3 cells at 72 hours after EV or STING plasmid electroporation. Data is represented as relative luminescence units. Data (A-B, E-F) are presented as mean ± SD. * indicates p<0.05; ** indicates p<0.01; *** indicates p<0.001 by Student’s t-test.
    Sting Inhibitor H 151, supplied by InvivoGen, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/sting+inhibitor+h151/H-151/pm42140967-273-31-35
    Average 96 stars, based on 1 article reviews
    sting inhibitor h 151 - by Bioz Stars, 2026-09
    96/100 stars
    		  Buy from Supplier
    sting inhibitors h 151  (InvivoGen)
    96
    InvivoGen sting inhibitors h 151
    STING loss- and gain- of function studies support a growth-restraining role in PEL. (A) BCBL1 and (B) BC3 cells were treated with 5 µM <t>H151</t> for 72 hours and subjected to CellTiter-Glo assay. Western blot of STING overexpression 48 hours after electroporation of 100 ng pcDNA3.1 (EV) or 50-100 ng STING plasmid in (C) BCBL1 and (D) BC3 cells. CellTiter-Glo assay in (E) BCBL1 and (F) BC3 cells at 72 hours after EV or STING plasmid electroporation. Data is represented as relative luminescence units. Data (A-B, E-F) are presented as mean ± SD. * indicates p<0.05; ** indicates p<0.01; *** indicates p<0.001 by Student’s t-test.
    Sting Inhibitors H 151, supplied by InvivoGen, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/sting+inhibitor+h151/H-151/pm41880208-51-0-10
    Average 96 stars, based on 1 article reviews
    sting inhibitors h 151 - by Bioz Stars, 2026-09
    96/100 stars
    		  Buy from Supplier

    Image Search Results


    STING loss- and gain- of function studies support a growth-restraining role in PEL. (A) BCBL1 and (B) BC3 cells were treated with 5 µM H151 for 72 hours and subjected to CellTiter-Glo assay. Western blot of STING overexpression 48 hours after electroporation of 100 ng pcDNA3.1 (EV) or 50-100 ng STING plasmid in (C) BCBL1 and (D) BC3 cells. CellTiter-Glo assay in (E) BCBL1 and (F) BC3 cells at 72 hours after EV or STING plasmid electroporation. Data is represented as relative luminescence units. Data (A-B, E-F) are presented as mean ± SD. * indicates p<0.05; ** indicates p<0.01; *** indicates p<0.001 by Student’s t-test.

    Journal: Frontiers in Immunology

    Article Title: STING inhibits viral lytic reactivation and cell growth in primary effusion lymphoma

    doi: 10.3389/fimmu.2026.1823240

    Figure Lengend Snippet: STING loss- and gain- of function studies support a growth-restraining role in PEL. (A) BCBL1 and (B) BC3 cells were treated with 5 µM H151 for 72 hours and subjected to CellTiter-Glo assay. Western blot of STING overexpression 48 hours after electroporation of 100 ng pcDNA3.1 (EV) or 50-100 ng STING plasmid in (C) BCBL1 and (D) BC3 cells. CellTiter-Glo assay in (E) BCBL1 and (F) BC3 cells at 72 hours after EV or STING plasmid electroporation. Data is represented as relative luminescence units. Data (A-B, E-F) are presented as mean ± SD. * indicates p<0.05; ** indicates p<0.01; *** indicates p<0.001 by Student’s t-test.

    Article Snippet: BCBL1 and BC3 cells were treated with 5 μM STING inhibitor H151 (MedChemExpress cat# Hy-112693) ( ) prepared in DMSO for 72 hours prior to CellTiter-Glo assay.

    Techniques: Glo Assay, Western Blot, Over Expression, Electroporation, Plasmid Preparation